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En estudios en animales los efectos se observan en das

Reagents Dulbeccos Modified Eagle Medium (DMEM) including 4.5g/L glucose, L-glutamine, and sodium pyruvate was purchased from Corning (Mediatech, Inc., Manassas, VA) to culture mammalian cells

Four patients (~20%) had a reduced frequency of cytotoxic CD56 dim NK cells together with an altered BM NK transcriptome that featured enriched expression of genes encoding enrichment of inhibitory receptors ( KLRB1 and KLRC1 ) and decreased expression of genes encoding activating receptors such as FCGR3A (CD16), NCR3 (NKp30), and CD226 (DNAM1)

It has virtually no direct blood supply
