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In MS, CoQ 10 controls the symptoms associated to the neurological disease, such as fatigue and depression, but seems to be limited to relapsing-remitting of the MS

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In addition, the ratio of neuroprotective to neurotoxic kynurenine metabolites differs between healthy controls and ME/CFS patients [46], accompanied and probably often preceded by a general decrease in tryptophan [25, 74]

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