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Filters for grade A mechanism, indicating peer-reviewed publications to target relevant mechanisms in humans, and grade A trial or case data, indicated by two or more peer-reviewed publications describing benefit in well-designed placebo-controlled human trials, or one or more peer-reviewed publications reporting benefits in validated diagnoses were applied for inclusion in our review

Data from this study are available in a FAIR data repository (odc-tbi.org)

Although excessive sugar intake is considered a major cause of T2DM [2, 28], the exact mechanism by which high glucose causes -cell failure remains unclear