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It plays an integral role in a number of bodily functions, including DNA production and the formation and maintenance of red blood cells and nerve cells

PCPGs manifest a strong hypoxic-like signaling, abnormal mitochondrial morphology as well as DNA hypermethylation, which is increasingly recognized in SDHx-mutated PCPG [116]

The symptoms are: Low energy Chronic fatigue Weakness Light-headedness Heart palpitations and shortness of breath Pale skin Dental problems, such as mouth sores and bleeding gums Sore red tongue Yellowing of the skin Mouth ulcers Constipation, diarrhoea, nausea, loss of appetite, or gas Nerve issues such as tingling or numbness, muscle weakness, and difficulty walking Joint pain Vision loss Mental illness, memory loss, or behavioural changes Poor concentration Dr Aravinda further noted that serious clinical symptoms like dementia, weariness, mood disruption, and megaloblastic anaemia can result from severe vitamin B12 insufficiency

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