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Nitric oxide and energy production in articular chondrocytes

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They may also indirectly exert their antioxidant activity by stimulating endogenous antioxidant defense systems (e.g., glutathione peroxidase and superoxide dismutase) and/or inhibiting enzymes that generate large amounts of ROS, such as xanthine oxidase and NAD(P)H oxidase

306 A retrospective study also demonstrated that Sivelestat had beneficial effects on sepsis-related ARDS
