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279 Litvinchuk et al
Eur J Ther
Furthermore, the availability of numerous natural and synthetic Nrf2 inducers isothiocynate (sulforaphan), polyphenols (curcumin and resveratrol), flavonoids (Quercetin and kaempferol), and terpenoids (Carnosic acid) is one of the major advantage for targeting this pathway (Wang et al., 2024)
28-30 These actions are mainly mediated by 2-adrenergic receptor subtypes 29,31 although other adrenergic-receptor-independent mechanisms, 28 vagomimetic, and humoral pathways contribute to the anti-inflammatory effect
