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Serotonin syndrome symptoms may include mental status changes (e.g., agitation, hallucinations, delirium, and coma), autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia), neuromuscular changes (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination), seizures, and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea)

Hearts from heterozygous (GPx1 +/ ) knockout mice were more susceptible to diastolic dysfunction following ischemia/reperfusion (I/R) injury than wildtype hearts [39] and GPx1 / hearts (from male mice) showed both contractile and diastolic dysfunction following I/R, with an increase in oxidative stress as measured by an increase in protein carbonylation [40]

After an additional 12 h of stirring at room temperature, the solution was introduced into 10 mL of deionized water while undergoing sonication

10.1097/CCM.0000000000004625 [DOI] [PMC free article] [PubMed] [Google Scholar] 254.Ghati A, Dam P, Tasdemir D, Kati A, Sellami H, Sezgin GC, et al