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To delve deeper into this connection, it is imperative to possess a comprehensive comprehension of the characteristics of vitamin B12, its absorption, and the process by which metformin could potentially hinder its absorption

If left untreated, a B12 deficiency can cause more severe health problems, including nerve damage, cognitive issues, and anaemia

[2] A few small studies and case reports have suggested that biotin supplementation might thicken or strengthen brittle nails in some individuals, but these studies often lack placebo control and involve oral biotin, not injections

PMID 23356970