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Bevacizumab in the treatment of metastatic breast cancer: Friend or foe

The tumor suppressor protein p53 increases the expression of the aspartate/glutamate transporter SLC1A3 and the arginine transporter SLC7A3 upon glutamine depletion, leading to resistance to treatments that deplete extracellular glutamine 114,115

Supplied in sterile vials to support consistent laboratory handling

Thus, it is reasonable to speculate that better neuronal function following CAR treatment may be associated with BBB protection and suppression of the ROS/NF-B/MMP-9 pathway
