Heme: The Lord of the Iron Ring
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bso inhibition glutathione The synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma The glutathione synthesis inhibitor buthionine
Description
Ferroptosis induction triggers immunogenic cell death (ICD) and the release of damage-associated molecular patterns (DAMPs), which promotes dendritic cell maturation and enhances CD8+ T cell cytotoxicity
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