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ACKNOWLEDGMENT The simulations in this work were done using the SCHOONER cluster of the University of Oklahoma and on TACC resources allocated under grant MCB20016 (National Science Foundation)
fluorescens (Lipase AsK, Amano), B
These dual stimuli trigger assembly of the NLRP3-ASC-caspase-1 complex, leading to caspase-1 activation
Subcutaneous injections are administered into fat under the skin, so instead of the needle going in at a 90-degree angle, the subcutaneous injection angle is at 45 degrees so that it pierces the skin but not the muscle tissue
