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In rats that received pentadecapeptide BPC 157 immediately after paracetamol, we found no lesions after 25 minutes or 3 hours post-paracetamol, and only mild lesions after 24 hours ( Table 1 ) and consistently less liver enzymes and ammonium serum values ( Table 2 )

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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Tepes M., Krezic I., Vranes H., Smoday I.M., Kalogjera L., Zizek H., Vukovic V., Oroz K., Kovac K.K., Madzar Z., et al

It has been reported that the myocardial infarction increases NOX2-derived ROS that activated apoptotic pathways such as Apoptosis signal-regulating kinase 1-p38 pathway ((ASK-1)-p38MAPK) and Ca 2+ /calmodulin-dependent protein kinase II (CAMKII)