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Moreover, the signal at m/z = 616 was present with moderate intensity and is assigned to the hemin molecule

doi: 10.1016/j.brainresrev.2010.04.009 113 Roman-PintosLMVillegas-RiveraGRodriguez-CarrizalezADMiranda-DiazAGCardona-MunozEG

Extensive persistent inflammation even when SARS-CoV-2-infected cells are only sporadically present at late stages of COVID-19 (Schurink et al., 2020) could also justify low GSH levels in association with over-abundance of cellular ROS, cellular oxidative damage, increased inflammation and cell death pathways activation seen in inflammaging (Zuo et al., 2019

Assuming a sequential reaction, where the enzyme, GPX, must bind to both substrates, ROS and GSH, for the reaction producing GSSG to occur and letting ROS and GSH to be the leading and following substrates, respectively, is the the reaction rate for GSSG
