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This pathway is hyperactivated in NF1-related tumours, and inhibition of MAPK kinase (MEK) was effective at controlling tumour size in a mouse model of NF1
Increased -SMA expression in primary lung fibroblasts from aged (24 months) C57BL/6 mice compared to young (8 months) C57BL/6 mice
Yale School of Medicine faculty profile (Kavli Institute)
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