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Description
The levels of glutathione in our body can decrease because of stress, poor nutrition, and aging
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These phenotypic changes occur without alteration of the NADP + /NADPH ratio but with accumulation of the terminal oxPPP product (and non-oxPPP substrate) ribose 5-phosphate as well with decreased levels of glycolytic metabolites, possibly due to impaired pentose overflow 135
Drossman DA, Dumitrascu DL: Rome III: New standard for functional gastrointestinal disorders
