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doi: 10.1136/gut.47.4.575
Shiota, Y
Although DCs are the most potent professional antigen-presenting cells, they can stimulate T cell activation to suppress tumor cell growth or become tolerant in certain TME to exhibit immunosuppressive properties
After a phase 1 clinical trial [99] and a phase 2 using an oral formulation, TLK199 appeared to be well tolerated and with some efficacy in the myeloplastic syndrome treatment [100]
