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It is well known that TM6SF2 and other genes are involved in the development of NASH [28,29,30]

In addition, vitexin significantly reduced hepatic macrophage infiltration, obviously downregulated the mRNA and protein expressions of hepatic SREBP-1c, FAS, ACC, and could significantly inhibit the expressions of TLR4/NF-B signaling in NAFLD mice ( Another metabolite, quercetin is also reported to protect the liver

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