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Heres the estimated time for the two Dupixent strengths, shown in milligrams per milliliter (mg/mL): 200 mg/1.14 mL pen or syringe: remove 30 minutes before injection 300 mg/2 mL pen or syringe: remove 45 minutes before injection Since Dupixent doesnt contain any preservatives, dispose of any unused solution left in the pen or syringe in your sharps container