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Description
Gmez-Ruiz and co-workers prepared a MSNs-based nanoplatform for delivery of a cocktail of agents (leptin and pioglitazone) to fight against amyotrophic lateral sclerosis
It was observed that IR treatment significantly decreased the chimeric percentages of donor-derived PB, BM cells, LK, LSK, and HSCs in recipient mice compared to non-IR-treated group
In addition to revealing a general approach to investigating rare genetic diseases, we demonstrate the biochemical foundations of therapeutic strategies targeting GPX4
Furthermore, we confirmed GLP-1MK-801-mediated target engagement with NMDA receptors in GLP-1-receptor-positive neurons in the arcuate nucleus using electrophysiological recordings of isolated NMDA receptor currents
