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Description

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Understanding the contribution of metabolism to Mycobacterium tuberculosis drug tolerance

The plasma is completely saturated at doses of 400 mg daily and higher, producing a steady-state plasma concentration of approximately 80 M

Importantly, microbial adaptation within oxidative and hypoxic wound microenvironments is increasingly recognized as a driver of antibiotic resistance and delayed tissue regeneration, highlighting the therapeutic advantage of redox-responsive scaffolds capable of modulating local ROS dynamics and infection progression