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In most cases, LOX may not be the primary driver of ferroptosis, but it may contribute to the initiation or spread of damage

J Mol Endocrinol (2022) 69(4):T1324

10.1158/0008-5472.CAN-08-1321 [DOI] [PubMed] [Google Scholar] Barbosa N

More recent findings suggest that NAC corrects the alterations in glutamate homeostasis associated with drug addiction by inducing GLT1, a glial transporter that clears extracellular glutamate and inhibits the activation of extrasynaptic receptors that are involved in the induction and expression of maladaptive synaptic plasticity, such as mGlu5 receptors [117]