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The literature further indicates that the simultaneous intake of acidsuppressing medications (such as proton pump inhibitors [PPIs] and histamine 2 receptor antagonists [H2RAs]) with metformin increases the risk of vitamin B12 deficiency in individuals with T2D [44-48]
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Drug delivery using various nanosystems, such as liposomes 80 , dendrimers 81 , and polymeric nanoparticles 82 , offer promising advantages
