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Supports collagen, elastin, and connective tissue health

Additionally, among SASP factors, there are growth factors such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and insulin-like growth factor 1 (IGF-1), which, when secreted into the environment by senescence cells, stimulate the repair and regeneration of surrounding tissues [13]

An initial report showed that administration of exogenous GDF11 at 0.1 mg/kg to aged mice reduced cardiac hypertrophy, like the heterochronic parabiosis experiments [15]

Secondary applications with emerging evidence include wound healing in patients with non-healing tissue, hair follicle stimulation, and early-stage research into cardiac recovery effects following the 2026 human trial data on Thymosin Beta-4