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Besides AD, DFO alone or co/treatment with ferrostatin (Fer-1, inhibitor of lipid peroxidation) also improved -synuclein-induced pathology in a PD animal model (Febbraro et al., 2013)
Mutat Res 478(12):2343 Klungland A, Hoss M, Gunz D, Constantinou A, Clarkson SG, Doetsch PW, Bolton PH, Wood RD, Lindahl T (1999) Base excision repair of oxidative DNA damage activated by XPG protein
This can impair pronuclear development, embryo quality, and implantation outcomes
doi:10.1186/1757-1626-1-189 Goto F, Nakai K, Kunihiro T, Ogawa K
