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Secondly, ketone bodies are metabolized in mitochondria, resulting in less NAD + consumption and an increase in the NAD + /NADH ratio in the cytoplasm (144)

Guo Y-L, Wu P, Jiang W-D, Liu Y, Kuang S-Y, Jiang J et al (2018) The impaired immune function and structural integrity by dietary iron deficiency or excess in the gill of fish after infection with Flavobacterium columnare : regulation of NF-B, TOR, JNK, p38MAPK, Nrf2 and MLCK signalling