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The structure of a zeta class glutathione S-transferase from Arabidopsis thaliana: characterisation of a GST with novel active-site architecture and a putative role in tyrosine catabolism

In this process, GSTU17 acts as a negative component of the stress-mediated signal transduction pathways

converts superoxide to hydrogen peroxide and oxygen 1

In this phase II trial involving 50 men with metastatic castration-resistant prostate cancer (mCRPC), the administration of docetaxel combined with oral curcumin (6 g/day for 7 days every 3 weeks) demonstrated no significant differences in progression-free survival (PFS), PSA response, overall survival, or quality of life (QoL) when compared with placebo, despite high compliance and confirmed curcumin absorption