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Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats

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None of the animals were sacrificed for this study

A preliminary study found that daily consumption of a mixture of 2 L of water, 4 ounces of reconstituted lemon juice, and an artificial sweetener increased urine citrate concentrations and reduced stone formation in people with hypocitraturia-related kidney stones (Kang 2007)