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Role of Sirtuins in Maintenance of Genomic Stability: Relevance to Cancer and Healthy Aging

To this end, researchers have developed or screened a range of drugs and compounds capable of inhibiting ferroptosis through various approaches and have validated their neuroprotective effects using various disease models (Table III)

GPX3, similar to GPX1, is located at a low level of the selenoprotein level and is sensitive to selenium content in the body, so it is often used as a biological marker to measure selenium content in the body

Glutathione is a tripeptide made of three amino acids: cysteine, glutamic acid, and glycine
