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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, et al

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Biol Psychiatry 79(7):586594 Takata F et al (2021) Blood-brain barrier dysfunction amplifies the development of neuroinflammation: understanding of cellular events in brain microvascular endothelial cells for prevention and treatment of BBB dysfunction

Furthermore, in mice with HCC xenografts, treatment with xentuzumab (an IGF-neutralizing monoclonal Ab [mAb]) either as a single agent or in combination with sorafenib (which is routinely used in the treatment of liver cancer) reduced tumor growth rate and improved survival compared with vehicle-treated or sorafenib-treated controls