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Front Microbiol 9:67
Also, prior to screening with an optimized AlphaScreen/AlphaLISA assay, it is critical to evaluate the results of a plate treated with only DMSO and control compound(s)
A study in 2022 used this model to screen out a novel ALK5 inhibitor, TP-008, which reduced collagen deposition in mouse pulmonary fibrosis models by 70% (Luttens et al., 2025)
All of this has produced water that has dogged the Malawi cichlid enthusiasts, as they have needed to add all kinds of products to harden and buffer the water, but for characin enthusiasts, this soft, low-carbonate water has been like liquid gold
