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[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Glascock J., Sampson J., Connolly A.M., Darras B.T., Day J.W., Finkel R., Howell R.R., Klinger K.W., Kuntz N., Prior T., et al

Indeed, the PDH complex, which decarboxylates glycolytically derived pyruvate to acetyl coenzyme A and links cytoplasmic glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle, is modulated by reversible phosphorylation by PDH kinase (PDK)

ACC is a vital enzyme in fatty acid synthesis that can catalyze the carboxylation of acetyl-CoA to malonyl-CoA [17]

Sometimes, though, a stronger odor is noticed in people with one copy of a mutation, depending on diet and the gut microbiome