l carnitin hashimoto Hashimoto's Thyroiditis and the Keto Diet Frontiers | Association between fatigue,

L-carnitine does this by interacting with both the membrane phospholipids and their proteins, thus preventing the loss of mitochondrial membrane integrity

Carnitine supplementation can help restore these levels, particularly in people with higher metabolic demands or those following plant-based diets that provide limited dietary carnitine

Notably, at physiological concentrations, TMAO can enhance the integrity of the bloodbrain barrier through the tight junction regulator annexin A1, limit the reactivity of astrocytes and microglia, and protect the cognitive function of mice from inflammatory challenges

Hepatology 1997;25:148-53