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In addition to being synthesized by cardiomyocytes and known to modulate vascular permeability and dilation/constriction, NPPC is also produced locally by Sertoli cells in the testis and serves in an autocrine manner (80)

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Studies have examined BPC-157 in models of gastric lesions, intestinal anastomosis, and inflammatory bowel conditions in animal subjects (Sikiric et al., Journal of Physiology-Paris, 2003)

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Nathan C, Ding A

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4c.2: Initial dosage and titration

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