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Moreover, tamoxifen was found to induce the tamoxifen-activating enzymes that turn out to cause excessive formation of harmful metabolites and persistence of toxic effects (Pathak et al ., 1996)
[PubMed] [Google Scholar] Sun T., Yang W., Toprani S.M., Guo W., He L., DeLeo A.B., Ferrone S., Zhang G., Wang E., Lin Z., Hu P., Wang X
These include the liver, lungs, and skin

Kayser S, et al
