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Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection

6.3 Mitochondrial dysfunction and oxidative stress A key driver of downstream injury cascades in TBI involves mitochondrial impairments and the generation of oxidative stress (Hakiminia et al., 2022)

It is exemplified by the Ag85B antigen, whose immunogenicity has been found to compromise BCG vaccine efficacy by activating regulatory T cell responses and macrophage exhaustion pathways
