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10.1016/j.celrep.2017.07.062 56

Furthermore, extracellular matrix (ECM), including elastin, collagen, and proteoglycans, tethers the parenchymal compartments to the airway and affects the tissue mechanics and airway smooth muscle contraction

Although the relationship between sleep and oxidative stress is still under intense investigation, several studies provide evidence that wakefulness represents an oxidative challenge for the brain (DAlmeida et al

These two enzymes are part of the CYP450 system, all of which require Mg2+
