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The high-carnitine diet down-regulated the mRNA levels of several lipolytic genes ( CPT1A , ATGL and HSL ), in agreement with the increased lipid content in muscle

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L-Carnitine is a naturally occurring molecule synthesised endogenously from lysine and methionine, and it plays a critical role in how cells transport and oxidise fatty acids for energy

Conclusions In conclusion, L-Carnitine in combination with L-leucine and creatine, significantly enhanced lean muscle mass and functional strength particularly in the lower legs, likely due to an improved protein anabolism through the mTOR pathway