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Furthermore, Western blot analysis showed an efficient 74.48% reduction in CYP2E1 in the total heart extract of Cyp2e1 -KO rats (Fig

When drug tolerance sets in, individuals will often experience an uncontrollable urge to obtain more substances

doi: 10.1016/j.esxm.2022.100562
Russo et al ., 1999), 2) direct genotoxic effects through metabolic activation of estrogens (Liehr, 1998
