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Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless

Glutathione peroxidase 4 (GPX4) uses reduced glutathione as a substrate to reduce oxidized lipids to normal lipids, preventing the accumulation of peroxides, and thus inhibiting ferroptosis (20)

It contributes to increased levels of glutathione , one of the most important endogenous antioxidants
