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Peptic ulcers are the most common cause of acute upper GI bleeding
Excessive Fe 2+ can react with hydrogen peroxide (H 2 O 2 ) to produce and accumulate reactive oxygen species (ROS)
Jandric I, Vrcic H, Jandric Balen M, et al
Specifically, NPY and Y1 receptor knock-out mice showed decreased eosinophils in the bronchoalveolar lavage fluid, as well as decreased circulating immunoglobulin E (IgE) levels, compared to wild-type mice under allergic conditions [178]
