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While GSH is essential for normal redox homeostasis, its upregulation in tumor cells contributes to chemoresistance and poses a challenge to effective cancer treatment

Notch3, the third subtype of the Notch family, can regulate tumor maintenance and affect tumor chemotherapy resistance [177]

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Store lyophilized material at 4 F (20 C) or below in a sealed vial Allow the vial to reach room temperature before opening to prevent condensation Protect the peptide from prolonged exposure to light, heat, and humidity Use sterile laboratory equipment and appropriate aseptic technique during preparation Avoid repeated freezethaw cycles which may affect peptide stability Label all reconstituted samples with preparation date, solvent type, and concentration Following consistent handling procedures helps support reproducible results in biochemical assays and experimental model systems