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Additionally, NNMT has been shown to play a causal role in the development of T2D through quantitative trait locus mapping in mice (Yaguchi et al., 2005)

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The same group later identified the enzyme as manganese-dependent leucyl aminopeptidase (synonyms, cytosolic aminopeptidase, leucine aminopeptidase, leucine aminopeptidase 3, proline aminopeptidase, and peptidase S

It also established a U.S
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