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Based on Surveillance, Epidemiology, and End Results (SEER) data from CCA diagnoses between 2001 and 2017, the estimated 5-year mortality rate is 80.1% (Javle et al., 2022)
The threshold concentration for tubular reabsorption (above which the fractional reabsorption begins to decline) is about 4060 mol/L, which is similar to the endogenous plasma L-carnitine level
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[210] have described an alternative calpain-dependent pathway of necroptosis induced by valproic acid (VPA) in the neuronal cell culture
