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the General Program of National Natural Science Foundation of China (No
Okeke et al., 2019)
In the MyD88 dependent- pathway, TLR binds with MyD88 at the toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (TIRAP) inducing the recruitment of the IL-1 receptor-associated kinase (IRAK) [45]
By the end of the study, subjects in the curcumin group had significantly greater insulin sensitivity and beta-cell function, as well as higher adiponectin levels than the placebo group (Chuengsamarn 2012)
