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It was suggested that RE may be created by an increase in HA and decrease in collagen fibrils via oxidative stress responses

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Butovsky, O

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Similar results were obtained in zebrafish (209)

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Downregulating PARP-1 protein hinders the action of NF-B and the expression of tumor-promoting proteins controlled by NF-B, thereby preventing the induction of parthanatos (Pazzaglia and Pioli, 2019)

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