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Distinctively expressed genes were used to draw heat maps and conduct the KEGG ontology enrichment analysis

doi: 10.1093/humupd/dmad031 51 ShiJXuQYuSZhangT

They also increase the activity of enzymes that degrade cartilage and reduce the production of protective antioxidant enzymes, leading to further cartilage degeneration

Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site