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Description
In young men, FOXO4 was predominantly found in the cytoplasm of Leydig cells, whereas in elderly men, it was primarily localized in the nucleus
This specifically affects the nucleus pulposus due to its high water (around 70%) and proteoglycan content compared to the annulus fibrosus
Digestion 56 (2), 9699
This is the same material that makes up your own cell membranes
