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This hypothesis derives from the fact that drugs, including phenylcyclohexylpiperidine (PCP), cause schizophrenia-like psychotic symptoms in humans by blocking the function of the NMDA receptor, and that such psychotic symptoms are difficult to diagnostically distinguish from schizophrenia ( Previous studies on schizophrenia has predominantly concentrated on dopaminergic and glutamatergic neurotransmitters

A: Most users see improvements within 3-6 weeks on a loading protocol of 1200-2400mg, 2-3 times per week

doi: 10.1016/j.molmed.2023.05.013 33 PanWZhangJZhangLZhangYSongYHanLet al

10.1016/s8756-3282(98)00180-x [DOI] [PubMed] [Google Scholar] Seiwerth S., Brcic L., Vuletic L