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Description
Another strategy relies on inhibition of the glycine transporter (sarcosine, bitopertin) or of D-amino acid oxidase (DAAO), the enzyme that metabolizes D-serine (sodium benzoate)
phenoxazine, right)
Acetylation modulates N-terminal autoproteolytic processing of SnCE1 The data shown above indicate lysine acetylation in wild type SnCE1 prohibits proteolytic processing, while all non-acetylated mutants, including SnCE1 Y212A and SnCE1 C256A, show proteolytic processing as visible by immunoblotting with a specific anti-SnCE1 antibody (Figs
11 May 2022
