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Description
Carbonyl cyanide m-chlorophenyl hydrazine renders the inner mitochondrial membrane permeable to H+, leading to membrane potential destabilisation on both sides of the inner mitochondrial membrane, and then, via the Pink1-Parkin pathway, which is specific for membrane potential destabilisation, the mitochondria undergo further membrane potential (MMP) hyperpolarisation, which generates ROS
Eunice Kennedy Shriver National Institute of Child Health and Human Development, September 8-9, 2008, Rockville, MD (NICHD) Pediatric studies of hydroxocobalamin
McEvoy, C
Free Radical Research, 42 , 978988
